Houston Wastewater Epidemiology's efforts in science and innovation involve an interdisciplinary collaboration of experts who are highly published. The following list of manuscripts detail work toward the development and management of a comprehensive wastewater monitoring system to target SARS-CoV-2, influenza, respiratory syncytial virus (RSV), mpox, and other pathogens.
Rebecca Schneider, Kaavya Domakonda, Sharmila Bhandari, Lauren Stadler, Katherine B. Ensor, Anthony Mulenga, Catherine D. Johnson, and Loren Hopkins. Implementing an Alert System for Communicating Actionable Wastewater Surveillance Results to School Communities, Houston, Texas, 2023-2024. Public Health Reports®. 2024;0(0). doi:10.1177/00333549241275408
Gwendolyn Johnson, Elizabeth Stevenson, Lauren Stadler, Kathy Ensor, Stephen Williams, Komal Sheth, Catherine Johnson, Loren Hopkins. Schools and Wastewater Surveillance: Practical Implications for an Emerging Technology to Impact Child Health. Health Promotion Practice. September 20, 2023. https://doi.org/10.1177/15248399231196857
Rebecca Schneider, Kirsten Weisbeck, Komal Sheth, Porter Sikes, Kaavya Domakonda, Lauren Stadler, Katherine B. Ensor, Rachel Shaw, Cody Berkobien, Allison Wheeler, Catherine D. Johnson, Corinne Lengsfeld, and Loren Hopkins. Assessment of Public Health Agency and Utility Training Needs for CDC National Wastewater Surveillance System Jurisdictions in the United States. Health Promotion Practice. 2024;0(0). doi:10.1177/15248399241275617
Komal Sheth, Loren Hopkins, Kaavya Domakonda, Lauren Stadler, Katherine B Ensor, Catherine D Johnson, Janeana White, David Persse, Edward Septimus. Wastewater Target Pathogens of Public Health Importance for Expanded Sampling, Houston, Texas, USA. Emerg Infect Dis. 2024 Aug;30(8):14-17. doi: 10.3201/eid3008.231564. PMID: 39043434; PMCID: PMC11286076.
Komal Sheth, Kaavya Domakonda, Kirstin Short, Lauren Stadler, Katherine B. Ensor, Catherine D. Johnson, Stephen L. Williams, David Persse, Loren Hopkins. A Novel Framework for Internal Responses to Detection of Pathogens in Wastewater by Public Health Agencies. Public Health Reports®. 2024;0(0). https://doi.org/10.1177/00333549241253787
Madeline Wolken, Michael Wang, Julia Schedler, Roberto H Campos Jr, Katherine Ensor, Loren Hopkins, Todd Treangen, Lauren B Stadler. PreK-12 school and citywide wastewater monitoring of the enteric viruses astrovirus, rotavirus, and sapovirus. Science of The Total Environment. Volume 931, 25 June 2024, 172683. https://doi.org/10.1016/j.scitotenv.2024.172683
Esther G Lou, Yilei Fu, Qi Wang, Todd J Treangen, Lauren B Stadler. Sensitivity and consistency of long-and short-read metagenomics and epicPCR for the detection of antibiotic resistance genes and their bacterial hosts in wastewater. Journal of Hazardous Materials. Volume 469, 5 May 2024, 133939. https://doi.org/10.1016/j.jhazmat.2024.133939
Katherine B Ensor, Julia C Schedler, Thomas Sun, Rebecca Schneider, Anthony Mulenga, Jingjing Wu, Lauren B Stadler, Loren Hopkins. Online trend estimation and detection of trend deviations in sub-sewershed time series of SARS-CoV-2 RNA measured in wastewater. Scientific Reports 14, 5575 (2024). https://doi.org/10.1038/s41598-024-56175-2
Sarah E Philo, Kara B De León, Rachel T Noble, Nicolette A Zhou, Rashed Alghafri, Itay Bar-Or, Amanda Darling, Nishita D'Souza, Oumaima Hachimi, Devrim Kaya, Sooyeol Kim, Katrin Gaardbo Kuhn, Blythe A Layton, Cresten Mansfeldt, Bethany Oceguera, Tyler S Radniecki, Jeffrey L Ram, Lauren P Saunders, Abhilasha Shrestha, Lauren B Stadler, Joshua A Steele, Bradley S Stevenson, Kyle Bibby, Alexandria B Boehm, Rolf U Halden, Jeseth Delgado Vela. Wastewater surveillance for bacterial targets: current challenges and future goals. Applied and Environmental Microbiology. 15 December 2023. https://doi.org/10.1128/aem.01428-23
Gwendolyn Johnson, Angelina Espàrza, Elizabeth Stevenson, Lauren Stadler, Kathy Ensor, Stephen Williams, Komal Sheth, Catherine Johnson, Loren Hopkins. Schools and Wastewater Surveillance: Practical Implications for an Emerging Technology to Impact Child Health. Health Promotion Practice. 20 September 2023. https://journals.sagepub.com/doi/abs/10.1177/15248399231196857
Camille McCall, Ryan A Leo Elworth, Kristine M Wylie, Todd N Wylie, Katherine Dyson, Ryan Doughty, Todd J Treangen, Loren Hopkins, Katherine Ensor, Lauren B Stadler. Targeted metagenomic sequencing for detection of vertebrate viruses in wastewater for public health surveillance. ACS ES&T Water 3 (9), 2955-2965. 9 August 2023. https://pubs.acs.org/doi/abs/10.1021/acsestwater.3c00183
Loren Hopkins, Katherine B. Ensor, Lauren Stadler, Catherine D. Johnson, Rebecca Schneider, Kaavya Domakonda, James J. McCarthy, Edward J. Septimus, David Persse, Stephen L. Williams. Public Health Interventions Guided by Houston's Wastewater Surveillance Program During the COVID-19 Pandemic. Public Health Rep. 2023 Jul 28:333549231185625. https://journals.sagepub.com/doi/abs/10.1177/00333549231185625.
Nicolae Sapoval, Yunxi Liu, Esther G. Lou, Loren Hopkins, Katherine B. Ensor, Rebecca Schneider, Lauren B. Stadler, Todd J. Treangen. Enabling accurate and early detection of recently emerged SARS-CoV-2 variants of concern in wastewater. Nat Commun 14, 2834 (2023). https://doi.org/10.1038/s41467-023-38184-3.
Madeline Wolken, Thomas Sun, Camille McCall, Rebecca Schneider, Kelsey Caton, Courtney Hundley, Loren Hopkins, Katherine Ensor, Kaavya Domakonda, Prashant Kalvapalle, David Persse, Stephen Williams, Lauren B. Stadler. Wastewater surveillance of SARS-CoV-2 and influenza in preK-12 schools shows school, community, and citywide infections. Water Research, 231, 119648. https://doi.org/10.1016/j.watres.2023.119648.
Loren Hopkins, David Persse, Kelsey Caton, Katherine Ensor, Rebecca Schneider, Camille McCall, Lauren B. Stadler. Citywide wastewater SARS-CoV-2 levels strongly correlated with multiple disease surveillance indicators and outcomes over three COVID-19 waves. Science of The Total Environment, 855, 158967. 10 January 2023. https://doi.org/10.1016/j.scitotenv.2022.158967.
Esther G. Lou, Priyanka Ali, Karen Lu, Prashant Kalvapalle, Lauren B. Stadler. Snapshot ARG Removal Rates across Wastewater Treatment Plants Are Not Representative Due to Diurnal Variations. ACS EST Water. December 15, 2022. https://doi.org/10.1021/acsestwater.2c00467.
Megan B. Diamond, Aparna Keshaviah, Ana I. Bento, Otakuye Conroy-Ben, Erin M. Driver, Katherine B. Ensor, Rolf U. Halden, Loren P. Hopkins, Katrin G. Kuhn, Christine L. Moe, Eric C. Rouchka, Ted Smith, Bradley S. Stevenson, Zachary Susswein, Jason R. Vogel, Marlene K. Wolfe, Lauren B. Stadler and Samuel V. Scarpino. Wastewater surveillance of pathogens can inform public health responses. Nat Med (2022), Commentary. https://doi.org/10.1038/s41591-022-01940-x.
Esther G. Lou, Nicolae Sapoval, Camille McCall, Lauren Bauhs, Russell Carlson-Stadler, Prashant Kalvapalle, Yanlai Lai, Kyle Palmer, Ryker Penn, Whitney Rich, Madeline Wolken, Pamela Brown, Katherine B. Ensor, Loren Hopkins, Todd J. Treangen, Lauren B. Stadler. Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater. (2022) Science of The Total Environment, Volume 833, 10 Aug 2022, 155059 https://doi.org/10.1016/j.scitotenv.2022.155059.
Camille McCall, Zheng N. Fang, Dongfeng Li, Andrew J. Czubai, Andrew Juan, Zachary W. Laturner, Katherine Ensor, Loren Hopkins, Philip B. Bedient, Lauren Stadler. Modeling SARS-CoV-2 RNA degradation in small and large sewersheds. (2022) Environ. Sci.: Water Res. Technol., 2022, 8, 290-300. https://doi.org/10.1039/D1EW00717C.
Zachary W. LaTurner, David M. Zong, Prashant Kalvapalle, Kiara Reyes Gamas, Austen Terwilliger, Tessa Crosby, Priyanka Ali, Vasanthi Avadhanula, Haroldo Hernandez Santos, Kyle Weesner, Loren Hopkins, Pedro A. Piedra, Anthony W. Maresso, Lauren B. Stadler. Evaluating recovery, cost, and throughput of different concentration methods for SARS-CoV-2 wastewater-based epidemiology. Water Research, Volume 197, 2021, 117043, ISSN 0043-1354, https://doi.org/10.1016/j.watres.2021.117043.
Nicolae Sapoval, Esther Lou, Loren Hopkins, Katherine B Ensor, Rebecca Schneider, Todd J Treangen, Lauren B Stadler. Enhanced Detection of Recently Emerged SARS-CoV-2 Variants of Concern in Wastewater. medRxiv 2021.09.08.21263279, https://doi.org/10.1101/2021.09.08.21263279.
Aaron Bivins, Devin North, Arslan Ahmad, Warish Ahmed, Eric Alm, Frederic Been, Prosun Bhattacharya, Lubertus Bijlsma, Alexandria B. Boehm, Joe Brown, Gianluigi Buttiglieri, Vincenza Calabro, Annalaura Carducci, Sara Castiglioni, Zeynep Cetecioglu Gurol, Sudip Chakraborty, Federico Costa, Stefano Curcio, Francis L. de los Reyes, Jeseth Delgado Vela, Kata Farkas, Xavier Fernandez-Casi, Charles Gerba, Daniel Gerrity, Rosina Girones, Raul Gonzalez, Eiji Haramoto, Angela Harris, Patricia A. Holden, Md. Tahmidul Islam, Davey L. Jones, Barbara Kasprzyk-Hordern, Masaaki Kitajima, Nadine Kotlarz, Manish Kumar, Keisuke Kuroda, Giuseppina La Rosa, Francesca Malpei, Mariana Mautus, Sandra L. McLellan, Gertjan Medema, John Scott Meschke, Jochen Mueller, Ryan J. Newton, David Nilsson, Rachel T. Noble, Alexander van Nuijs, Jordan Peccia, T. Alex Perkins, Amy J. Pickering, Joan Rose, Gloria Sanchez, Adam Smith, Lauren Stadler, Christine Stauber, Kevin Thomas, Tom van der Voorn, Krista Wigginton, Kevin Zhu, and Kyle Bibby. Wastewater-Based Epidemiology: Global Collaborative to Maximize Contributions in the Fight Against COVID-19. Environmental Science & Technology 2020 54 (13), 7754-7757. https://pubs.acs.org/doi/10.1021/acs.est.0c02388.
L.B. Stadler, K.B. Ensor, J.R. Clark, P. Kalvapalle, Z.W. LaTurner, L. Mojica, A. Terwilliger, Y. Zhuo, P. Ali, V. Avadhanula, R. Bertolusso, T. Crosby, H. Hernandez, M. Hollstein, K. Weesner, D.M. Zong, D. Persse, P.A. Piedra, A.W. Maresso, L. Hopkins. Wastewater Analysis of SARS-CoV-2 as a Predictive Metric of Positivity Rate for a Major Metropolis. medRxiv 2020.11.04.20226191; https://doi.org/10.1101/2020.11.04.20226191.
Google Scholar
Katherine Ensor, Ph.D. https://scholar.google.com/citations?user=0MCwHpQAAAAJ&hl=en&oi=sra
Loren Hopkins, Ph.D. https://scholar.google.com/citations?user=b65vQuAAAAAJ&hl=en
Rebecca Schneider, MS https://scholar.google.com/citations?hl=en&user=nzTYTO8AAAAJ
Komal Sheth, MPH https://scholar.google.com/citations?user=l75dFx4AAAAJ&hl=en
Lauren Stadler, Ph.D. https://scholar.google.com/citations?user=w8n_2aIAAAAJ&hl=en
Todd Treangen, Ph.D. https://scholar.google.com/citations?user=N5irv88AAAAJ&hl=en